The NIH Pediatric Research using Integrated Sensor Monitoring Systems (PRISMS) program was launched in 2015 to develop sensor-based, integrated health monitoring systems for measuring environmental, physiological, and behavioral factors in epidemiological studies of pediatric asthma, and eventually other chronic diseases.
The University of Utah PRISMS informatics center is developing a Federated Integration Platform — a distributed information system for clinical and translational research that will help to integrate, process, visualize, and securely transmit study data for the PRISMS program. Our goal is to provide an effective, flexible and open access approach to collecting and managing high-resolution data from sensors, based on logical data models for the clinically relevant exposome (environmental exposure information) that can be integrated with clinical data. This provides key infrastructure for the PRISMS program.
The center includes three major projects: (1) a platform for getting data from sensors, getting other study data, and displaying information at the study participant’s home; (2) a high-resolution data integration platform based on the CCTS OpenFurther architecture; (3) a platform to support clinical research in pediatric asthma.
The PRISMS program includes sensor development centers, a data coordinating center, and two informatics platform centers (ours in Utah, and one at UCLA). We are collaborating across the PRISMS centers and with other NIH-supported projects that are related to health and environmental exposures, to define standard representations for PRISMS information